Diabetic Neuropathy Home A-Z Health Information Health Library A-Z Diabetic Neuropathy Overview Diabetic neuropathy refers to a condition in which high blood sugar levels lead to nerve damage. It can affect various body parts such as the digestive system, heart, and blood vessels. Symptoms Symptoms like pain, tingling, and numbness, often in the legs and feet. Diagnosis Physical exam, nerve conduction studies, and blood tests to assess blood sugar control. Treatment Treatment for diabetic neuropathy involves managing symptoms and regulating blood sugar levels. Medications, physical therapy, and lifestyle changes can help alleviate pain and enhance the quality of life. Early diagnosis and management are crucial for preventing severe complications and for maintaining nerve function.The American Diabetes Association suggests starting screening for diabetic neuropathy right after a person is diagnosed with type 2 diabetes or 5 years after being diagnosed with type 1 diabetes. It is advised to have a screening once every year after that.