Well Women Centre

Our ART team comprises highly experienced in vitro fertilisation (IVF) specialists, embryologists, andrologists, counsellors, reproductive technology experts, nurses, and ancillary staff. The nursing staff, counsellors, and administrative personnel are equipped to take all the patient’s needs into consideration. Equipped with the correct experience and the right disposition, we will provide you with world-class facilities and treatment options to fulfil your dreams.

Facilities:

• Hormone tests, pre-IVF testing, fertility check-up package
• Semen testing using Computer-Assisted Semen Analysis (CASA)
• DNA fragmentation index (DFI) testing
• M-SOME: Motile Sperm Organelle Morphology Testing
• Ovarian reserve testing
• Assessment of embryo quality using a no-touch closed environment technique with video documentation
• Selection of the best embryos for implantation utilising artificial intelligence & deep-machine learning
• Electronic witnessing system to document all procedures in the laboratory
• Alarm system for the cryopreservation units
• Radio frequency identification (RFID) for the cryotanks
• Timelapse technology for visualising the developmental processes of embryos
• Vitrification & slow freezing for eggs, embryos, sperms, and testicular tissues and ovarian tissue freezing
• Electronic recording of all processes & procedures, including the history and reports of patients
• TV systems for video demonstration

Many young women are facing the challenge of low ovarian reserve, i.e., diminished eggs production. Lifestyle and environmental factors, such as the use of plastics and other products containing endocrine-disrupting chemicals, are major contributors to this condition. A common observation during IVF is that women with low ovarian reserve produce fewer eggs and/or low-quality eggs, resulting in the need for multiple IVF cycles; this is associated with lower chances of successful embryo implantation and sometimes, resorting to the use of donor eggs.

Our aim is to enhance your reproductive potential before you undergo the IVF cycle. We will guide you on making healthy choices, implementing lifestyle & dietary changes, and taking antioxidant medications that can help enhance your chances of conception.

We will also advise you whether intraovarian PRP therapy will benefit you. PRP therapy is safe to use as it is prepared from your own blood. After processing the PRP under sterile conditions in the laboratory, we will inject it into your ovary. This can be done either before starting an IVF cycle or during egg recovery. The injection of PRP into the ovary may be repeated 2 to 3 times depending on your response. Research has elucidated the beneficial use of PRP. To improve the quality of your eggs, we may recommend some antioxidants prior to your IVF cycle.

Egg and embryo cryopreservation represent methods for biological insurance, given that reproductive function declines with age. A woman is said to be the most fertile between 24 to 34 years of age; usually, fertility starts to decline post the age of 36 years. Fecundity rapidly declines after the age of 40. Fertility preservation through egg freezing or embryo cryopreservation offers a chance to preserve your reproductive potential before fertility declines. If you wish to postpone childbearing, it is important that you consult us for guidance regarding suitable options. The size of your ovaries, antral follicle count, i.e., the number of follicles in both the ovaries, and the serum anti- Müllerian hormone (AMH) level will help us ascertain your reproductive potential and whether you should delay childbearing. This is particularly important for women who want to delay having a baby for a few years, especially if they are in their early and mid-thirties. In such cases, freezing eggs or embryos is a wise choice. We will guide you and help you make the right choices in this regard. Furthermore, women with some forms of cancer may also benefit from oocyte and embryo freezing; these procedures will be performed under the guidance of their oncologist(s) and our team.

In cases where the time from cancer diagnosis to the start of chemotherapy is short, ovarian tissue or ovarian cortex freezing can help; this is also a good option for young girls with Turner syndrome. Our team places high importance on oncofertility, for which we have an international collaboration with Prof. Dr. Claus Anderson, who has extensive expertise in this field.

• Orthotopic transplantation: The implantation of ovarian tissue inside the peritoneal cavity, into the remaining ovary, ovarian fossa, or into the broad ligament.
  Advantages: It can lead to live births even through spontaneous pregnancies. At this time, orthotopic transplantation is the method of choice when live birth is the goal of auto transplantation. The recovery of endocrine function is observed in over 95% of cases, beginning 2–9 months after grafting; endocrine functionality is sustained for as long as 7 years.
• Heterotopic transplantation: The implantation of ovarian tissues into locations other than the peritoneal cavity, such as the subcutaneous abdominal wall, the region beneath the peritoneum, the rectus muscle, and/or the forearm.
  Advantages: This is a simple, cost-effective, and minimally invasive procedure. It is a valuable option when pelvic adhesions are present, which makes orthotopic transplantation unsuitable. This method is also preferred when the only goal is the recovery of natural endocrine function.

Male factor infertility accounts for 50% of infertility cases. We offer fully integrated diagnostic and treatment-oriented services for male infertility. Our team of experts includes andrologists, IVF specialists, counsellors, and embryologists to help patients with various aspects of fertility evaluation and treatment. Our expertise covers all aspects associated with the diagnosis, prevention, and treatment of male infertility.

Laboratory Services:

• Automated CASA
• DNA fragmentation index testing
• M-SOME
• Semen analysis based on the WHO manual (editions V and VI)
• Karyotyping
• Cystic fibrosis transmembrane receptor (CFTR) mutation testing
• Testing of Y microdeletions

Our endometriosis clinic is a fully integrated specialty clinic with expert laparoscopic surgeons, gynaecologists, and IVF specialists who offer medical, surgical, and IVF options, including laser and robotic surgery. Moreover, our specialists have global experience in bowel sparing surgery for endometriosis treatment.

Who can benefit?

• Women with bowel endometriosis

After menopause, women undergo many physical, hormonal, and mental changes. Our centre is fully equipped to help women during this difficult time. Our team consists of gynaecologists, reproductive endocrinologists, laparoscopists, physicians, counsellors, diabetologists, and life coaches.

After they turn 40, women encounter several additional stresses, such as looking after a growing family, caring for ageing parents, and demands from work and career. They may also experience symptoms such as bone loss, insomnia, night sweats, palpitation, and uneasiness. As the body faces the prospect of menopause, rest, exercise, and healthy eating should become the top priority. This is the time to improve fitness with muscle building & strength building exercises.

During their mid and late 40s, women may require oestrogen and progesterone therapy. Further, past the age of 60, it is critical for women to maintain their health and follow a healthy lifestyle to prevent degenerative diseases and cancer. Urinary bladder dysfunction, arthritis, or memory loss could also occur at this stage. Hence, timely treatment and appropriate counselling are necessary to prevent these problems.