Overview
DLBD is progressive neurodegenerative brain disease refers to condition caused by alpha synuclein deposits in brain. These deposits are called Lewy bodies. It is accounted as the second most prevalent cause of dementia after Alzheimer’s disease.
- The exact cause is unknown
- Some genes may elevate the risk of developing DLDB
- Age >60 years
- Female sex
- Family history
- Visual hallucinations are the hallmark of DLDB
- Movement disorders like bradykinesia, rigidity, tremors
- Cognitive problems- dementia, confusion, agitation
- Fluctuation in sensorium
- Sleep disorders
- Behaviour and mood symptoms- depression, apathy, anxiety
Neurologist
- Clinical examination
- MRI brain showing atrophy predominantly in occipital areas
- PET scan to show hypometabolism in these areas
- Brain biopsy (not done routinely)
- Medications (cholinesterase inhibitors, antipsychotics, antidepressants)
- Speech, cognitive therapy
- Movement disorders treatment
- No specific cure
