Management Team

Nutcracker oesophagus

Overview

This condition also known as hypercontractile oesophagus or jackhammer oesophagus is characterised by excessively strong (and prolonged) oesophageal contractions, resulting in pain and dysphagia (difficulty swallowing). The contractions may be normal in frequency but are excessively forceful.

  • Neuromuscular dysfunction: Disrupted neural regulation of the oesophagus, including impaired inhibitory neurotransmission, may lead to hypercontractility.
  • Chronic acid reflux
  • Psychological stress
  • Oesophageal inflammation: Conditions like eosinophilic esophagitis or general esophagitis may disrupt normal motility.
  • Genetic predisposition
  • Gastroesophageal reflux disease (GERD)
  • Ageing
  • Dietary triggers: Certain foods and drinks, especially those that are spicy or acidic, may trigger or worsen symptoms.

  • Dysphagia (difficulty swallowing)
  • Intense chest pain that is occasionally confused with a heart attack
  • Sensation of food getting stuck in the throat
  • Heartburn (burning sensation in the chest)

  • Oesophageal manometry: This is the primary diagnostic modality for nutcracker oesophagus. Diagnosis is based on the detection of hypercontractile contractions.
  • Oesophageal high-resolution manometry (HRM): This is a more advanced form of manometry. It can provide a more detailed, topographic map of pressure changes in the oesophagus and may be particularly helpful in differentiating nutcracker oesophagus from other oesophageal motility disorders.
  • Endoscopy: It is typically normal in nutcracker oesophagus and is performed to exclude other structural or inflammatory causes (e.g., tumours, strictures, or GERD-related esophagitis).

  • Medications: Various medications are used to relax the oesophagus
    • Calcium channel blockers
    • Nitrates
    • Botulinum toxin injections
    • Prokinetic medications (e.g., metoclopramide, domperidone)
    • Antidepressants (to regulate oesophageal nerve activity)
  • Surgical myotomy: In some cases, myotomy (a procedure involving trimming the circular fibres of the lower oesophageal sphincter (LES) to facilitate movement of food along the food pipe may be considered (if conservative measures fail).
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