Substance related disorders Home A-Z Health Information Health Library A-Z Substance Related Disorders Overview Substance related disorders encompass mental disorders related to addictions caused by certain substances. Common substances linked to addiction include alcohol, tobacco, caffeine, opioid, cannabis, hallucinogens, stimulants, sedatives, sleeping aids, anxiolytics, and inhalants. Addiction involves psychological and physical dependence, where an individual feels compelled to use a substance to manage or prevent withdrawal symptoms driven by an intense cravings. These substances can negatively impact various organ systems, increasing the risk of serious illnesses. Additionally, pathological gambling, a form of non-substance addiction, may also occur in some individuals. Causes and risk factors Substance use disorder can run in families. Risk factors include:StressEnvironmental factorsTrauma Symptoms The symptoms include: Feeling elevatedHallucinationsIncreased heart rateAnxiousAltered visual and auditory perceptions Diagnosis Substance abuse is diagnosed through:Medical historyObservationPhysical examination Treatment Substance abuse treatment includes:MedicationsBehavioural therapies.