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Nuclear Medicine

Overview

The Department of Nuclear Medicine at Sir H. N. Reliance Foundation Hospital and Research Centre offers a wide range of services, including Diagnostic Nuclear Imaging and Targeted Radionuclide Therapies. This unique state-of-the-art Molecular Imaging facility in Mumbai has best-in-class infrastructure with state-of-the-art nuclear medicine equipment, led by a team of experienced Nuclear Medicine specialists - for precise diagnoses and treatment which is the philosophy of our institute.

Our Vision

We envision a transformative approach to healthcare that moves beyond traditional diagnostics to a more personalised model of medical care.

Through advances in the field of medicine, we can now  examine not only the structural details of organs via radiological scans, but also their functions and changes happening due to disease in real-time via functional imaging techniques in Nuclear Medicine.

Imaging the molecular processes within organs and tissues has allows precise understanding  of the metabolic activity, receptor expression, and cellular level changes in blood flow, detection of malignant disease, and various other pathological processes via PET-CT and Gamma camera scans. This helps to transform ‘Medical Care’ to ‘Personalized Medical Care’ by allowing precise diagnosis and hence direction towards the appropriate treatment – leading to improved outcomes of our patients.

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  • About Us
  • Our Technology
The Tower

Our Nuclear Medicine Specialists deliver world-class services focused on improving diagnostic results.

The department is equipped with best-in-class imaging devices - with highest sensitivity and resolution. The dedicated team ensure best clinical results as well as patient comfort and experience at every step.

The department is thoughtfully designed for ergonomic efficiency, following a patient-centred workflow to ensure a smooth and welcoming process for all patients.

The Tower

Siemens Biograph mCT Flow PET-CT

This hybrid PET/CT system at out department supports high levels of productivity with Time of Flight (TOF) technology and an intelligent imaging platform. The high resolution and high contrast definition of PET images with Time of Flight technology allows excellent delineation of even small tumor and capturing of precise anatomical detail.The inbuilt hybrid CT system features a 40-slice CT configuration, surpassing the standard 16-slice PET/CT scanners commonly available.

This advanced capability allows for high quality CT imaging alongside PET acquisitions, providing faster scan times, and minimizing patient radiation exposure, all while maintaining exceptional image quality.

Siemens T16 Symbia SPECT-CT Gamma Camera Imaging system

We have an advanced, integrated, fully automated high definition SPECT-/CT gamma camera with a 32 slice diagnostic CT at our department.

This gamma camera boasts the best-in-class image quality, with industry-leading sensitivity, delivering high-resolution images at a minimum dose and maximum speed.

IQ-SPECT - Special Feature - For Cardiac scans

The gamma camera at Sir H.N. Reliance Foundation Hospital has advanced IQ-SPECT technology for dedicated imaging of heart. It provides high quality Myocardial Perfusion Imaging (MPI). The special converging collimators along with special imaging processing enhances cardiac imaging, providing superior clarity at lesser dose of radiation, and lesser time – leading to better patient safety and higher patient comfort.

Therapy ward

We have a 2-bedded High-Dose Therapy ward for our Targeted Radionuclear Therapy patients. (also called Theranostic services).

Following some therapies such as high dose I131 therapy, patients need to be admitted in special rooms for radiation isolation and protection. We ensure that our patients receive careful monitoring, while ensuring their comfort and safety. Each room is designed to provide a comfortable and spacious stay, featuring ample lighting and a dedicated bathroom. The rooms are constructed in full compliance with international radiation safety standards and have received certification from India’s Atomic Energy Regulatory Board (AERB)

Our Services

Positron Emission Tomography Imaging - PET-CT scans:

  1. Whole body FDG PET-CT: For diagnosis and staging in oncology, detecting recurrence and monitoring response to therapy in various malignancies, evaluation of pyrexia of unknown origin, paraneoplastic syndromes, etc.
  2. FDG Cardiac PET: For myocardial viability and myocardial inflammation/infection
  3. FDG Brain PET-CT: For brain for diagnosis of Alzheimer's disease and various dementias, epilepsy, brain tumours, and other neurological conditions
  4. Ga68-DOTANOC/DOTATATE PET/CT (Somatostatin receptor PET/CT): For neuroendocrine tumours 
  5. 68-Ga – PSMA PET/CT: For evaluation of prostatic malignancy
  6. F18-DOPA PET (Fluorodopa PET)
    • F-DOPA Brain PET: For evaluation of Parkinsons disease and brain tumor imaging
    • F18-DOPA – Fluorodopa whole body PET: For tumor imaging
  7. Ga68-FAPI PET-CT: For imaging of pancreatic cancer, GI tract malignancies, head & neck cancer, hepatocellular cancer, others
  8. Ga68-Exendin scan: For imaging insulinoma
  9. Ga68-Pentixafor (CXCR4) PET-CT: For imaging myeloma and Functioning adrenal adenoma imaging
  10. Ga68-Trivehexin PET-CT: For imaging parathyroid adenoma, and head & neck and other tumors
  11. F18-Fluoride Bone PET: For benign, malignant and metastatic bone disease
  12. F18-FLT PET-CT (Fluothymidine PET-CT): For imaging brain tumor and other tumors
  13. F18-Choline PET-CT: For Parathyroid adenoma, other tumour imaging

Gamma Camera - with SPECT-CT (Single Photon Emission Computed Tomography, with inbuilt CT scanner)

  1. Thyroid scans (Tc-99m)
  2. Parathyroid scan
  3. Myocardial perfusion scan - Exercise or Pharmacological (Adenosine, Dobutamine)
  4. MUGA scan
  5. Pyrophosphate scan for cardiac amyloidosis
  6. Renal scans - DTPA/EC scans
  7. DMSA scans
  8. GFR evaluation
  9. Renal transplant scan
  10. Direct and Indirect Radionuclide Cysto-urethrography
  11. Ventilation/Perfusion (V/Q) scan for lungs
  12. Perfusion scans (MAA) for lung shunts, R-L shunt
  13. GE reflux scan (milk scan)
  14. Gastric emptying study – solid and liquid.
  15. Meckels’ Diverticulum scan
  16. Gastrointestinal bleed scan
  17. RBC blood pool scan
  18. Hepatobiliary (HIDA) scan
  19. Liver colloid scan
  20. MAA scan for hepatopulmonary syndrome
  21. MAA scan for TARE planning
  22. Bone scan
  23. Bone marrow scan
  24. Brain SPECT scan (cerebral perfusion).
  25. Dopamine Transporter Imaging using 99mTc TRODAT (For Parkinson’s disease)
  26. Radio-iodine whole body scan (I-131)
  27. I131-mIBG Scan
  28. Tumour imaging scans with TcSestamibi
  29. Post Radionuclide Therapy Scans - High Dose Iodine 131 scan, Lu177 Post Therapy scans
  30. Lymphoscintigraphy: For Lymphoedema, chylous leaks
  31. Sentinel Node Imaging
  32. Dacryoscintigraphy: For Lacrimal function
  33. Salivary scintigraphy 
  34. Testicular scan 
  35. Peritoneo-pleural shunt scan

A variety of tumors are now treated with Targeted Alpha and Beta particles in our High Dose Therapy ward.

  1. Radio-Iodine Therapy (I131 Radioactive Iodine): For Thyroid Cancer, For Graves disease, Toxic nodules, Nodular goitres
  2. PRRT – Lu177-DOTATATE Therapy: For Neuroendocrine tumors
  3. Lu177-PSMA Therapy: For Prostate Cancer
  4. Ac225 PSMA and Ac225 DOTATATE Therapy – Alpha Therapy with Actinium225labeled Molecules
  5. I131-mIBG Therapy: For Neuroblastomas, Paragangliomas, other tumors
  6. Y90-TARE (Transarterial Radio-embolization with Yttrium 90 microspheres): For Liver tumors, liver metastases
  7. Bone Pain Palliation Therapy – Sm153, Sr89: For relief from bone pain due to cancers

FAQs

Nuclear medicine is a medical specialty that uses radioactive medicines to assess bodily functions and to diagnose and treat disease.

Radiopharmaceuticals include special medications used in nuclear medicine to diagnose or treat various medical conditions. These medications contain small amounts of radioactive material, which allows doctors to take images of organs or target specific cells for treatment.

Radiopharmaceuticals play a vital role in modern healthcare because they:

  • Help diagnose diseases like cancer, heart conditions, and bone disorders
  • Allow doctors to monitor the function of organs such as the heart, kidneys, and thyroid
  • Assist in detecting tumours and infections at an early stage
  • Treat certain diseases, such as thyroid cancer, neuroendocrine tumours, prostate cancers or bone pain due to cancer

Depending on the procedure - radiopharmaceuticals are administered either by injection, swallowing, or inhalation. The radioactive material travels through the body to the targeted organ or tissue.

For diagnostic purposes, a special camera (Gamma camera or SPECT-CT scanner or PET-CT scanner) captures images of the organ as the radiopharmaceutical medication moves through the body. These images help doctors detect abnormalities or diseases.

For treatment, the radiopharmaceutical delivers radiation directly to the targeted cells (such as cancer cells), helping to shrink or destroy them.

  1. Before the Procedure: depending on the procedure, you may be asked to fast or avoid certain medications, depending on the type of scan or treatment. Always communicate with the Nuclear Medicine Department and your doctor for these instructions.
  2. After the Procedure: You can usually return to normal activities right after the procedure. Drinking extra fluids helps your body eliminate the radioactive material faster.
    In some procedures, you may have to avoid contact with family members, children, pregnant women and general public. See specific procedure descriptions for details.

The radiation from radiopharmaceuticals is typically low and only affects the specific area being studied or treated, minimising exposure to other parts of the body.

Radiopharmaceuticals are carefully regulated and used in very small, controlled amounts, making them safe for medical use. The body typically eliminates the radioactive material through urine or stool within a few hours or days after the procedure (depending on type of procedure). The benefits of accurate diagnosis and targeted treatment usually outweigh the minimal risks associated with radiation exposure.

Most patients do not experience side effects. Occasionally, some people may experience mild discomfort at the injection site. Allergic reactions are rare.

For therapeutic nuclear medicine, your doctor will discuss potential side effects, which may vary based on the specific treatment.

Yes, nuclear medicine is used safely for children. Paediatric doses are carefully calculated to minimise radiation exposure while still obtaining useful diagnostic or therapeutic results.

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